Your Lettuce Resistente Franchi is a HUGE hit in our Central Florida winter garden! It shrugs off diseases and pests, but we gave it a head start by using a soil substitute mix of perlite/vermiculite/coir/composted manure/lime/slow release organic fertilizer to minimize chances of infection by the myriad plant diseases here.. Haven't sprayed once! We selectively harvested leaves and thinned plants until the heads began to form, then started harvesting heads and replanting seeds. Great flavor and texture, reminiscent of heirloom lettuces. My wife normally prefers iceberg or buttercrunch but fell in love with Resistente. Mille Grazie!